In its long life DSE-724 has been involved in several high-profile assignments on behalf of the Dominion and has been commanded by clones of the Vorta Weyoun for most of its operational life. Currently commanded by Weyoun 13, DSE-724 is currently assigned to oversee monitoring of the Bajoran Wormhole.

Under the command of Administrator Kuzos and First Ikidik'tan, DST-321 has been commissioned as a testbed starship and incorporates enhanced technologies over its counterparts. DST-321's greatest innovation is a specialized stealth technology that, while not a cloaking device per se, minimizes the vessel's sensor signature. This technology, coupled with DST-321's Heavy Polaron Beam Cannons and speed, make the vessel ideal for hit and run attacks against targets and boarding operations.

While DST-321 is early in its operational life, the ship and crew have already proven themselves in raids against dissident worlds. DST-321 led an assault upon a renegade Dosi outpost and used its troops to recover the station for the Dominion. In its latest mission, DST-321 was instrumental in rescuing the Founder Odo and establishing a stronger peace between the Dominion and the Federation.

Sharing the same body design and structure as a Jem'Hadar Fighter, Dominion Scoutships are lightweight and easily replaceable vehicles originally considered by the Dominion as only a small step above replaceable drones. Through the influence of Odo, both Jem'Hadar fighters and scouts were refit to the highest standard, representing the best of their capabilities. Slightly larger than a Starfleet Polaris Class Runabout, Dominion Scoutships are effective short-range reconnaissance vessels but are often closely supported by larger motherships.

The Revenant was decommissioned by the Dominion in 2438 after three decades of dedicated service after taking severe damage in an assault by an unidentified enemy source. Soon after the vessel was secretly repaired under the direct orders of Odo himself and transferred to his personal command. The Revenant was once again severely damaged during Odo's investigation and destroyed by the Forebearer, the originator of the Founder species.

The eighth Federation starship to bear the name Enterprise, development of the Constitution IV Class was primarily a result of Starfleet forces being outmatched and outmaneuvered by technologically sophisticated opponents in the late 24th and early 25th Centuries. Enterprise was constructed at San Francisco Fleet Yards in honor of the U.S.S. Enterprise NCC-1701 and launched in 2439.

Following its launch, Enterprise was assigned to a five-year mission of exploration. During its first assignment, Enterprise was ordered to Starbase 419 following contact between Starfleet's Forward Observation Zone and the Dominion. Enterprise was ordered to the Gamma Quadrant to investigate and located a damaged Dominion vessel. Due to the Enterprise's assistance a brokered peace treaty between the Federation and the Dominion authorized Enterprise to remain in the Gamma Quadrant on a five-year mission of exploration.

Built at the Baikonur Orbital Complex, Earth, Galileo was originally assigned to a survey mission within the Briar Patch. One year into its mission, Galileo encountered a hidden Son'a outpost deep within the Briar Patch and was able to hide from Son'a vessels for over two months before escaping and contacting reinforcements. Awarded for its efforts in protecting the Ba'Ku, Galileo was transferred from the Briar Patch to serve as a mission support craft for the Enterprise during its five-year exploratory mission.

Originally intended as a patrol ship for the Cardassian Demilitarized Zone, the Copernicus was configured with enhanced sensors suites and laboratories to enable it to conduct research missions within the Cardassian Sector. During an assignment to update navigational records of the Badlands, Copernicus located a renegade Alpha Jem'Hadar outpost within the region. Aiding a Starfleet Task Group in dismantling the Jem'Hadar operation, the Copernicus was able to conclude its mission without further incident.

Following the conclusion of its survey mission, Copernicus was selected by Starfleet Command to replace the starship U.S.S. Bougainville as the mission support vessel for the Gamma Quadrant Forward Observation Zone.